Madelon Vriesendorp (born 1945, Bilthoven) is a Dutch artist best known as one of the co-founders of the Office of Metropolitan Architecture (OMA) in the early 1970s (together with Rem Koolhaas and Elia Zenghelis and Zoe Zenghelis).
She was the wife of architect Rem Koolhaas.
She is best known for the painting "Flagrant Delit" which was used as the cover image for Delirious New York, written by Rem Koolhaas and first published in 1978.
Her largest piece of art is the painting on the stage tower of the Netherlands Dance Theatre in The Hague.
"The World of Madelon Vriesendorp: Paintings/Postcards/Objects/Games" was a 40-year retrospective exhibition of the artist's career, curated by Shumon Basar and Stephan Trüby. It originated at the Architectural Association School of Architecture, London in 2008, and then toured to Aedes, Berlin; the Venice Biennale of Architecture; and finally the Swiss Architecture Museum, Basel. It was accompanied by a richly illustrated catalogue, and had contributions from Beatriz Colomina, Douglas Coupland, Hubert Damisch, Teri Wehn-Damisch, Zaha Hadid, Charles Jencks, Charlie Koolhaas, Hans Ulrich Obrist, Brett Steele and Fenna Haakma Wagenaar.
Madelon Vriesendorp lives in London and has two children.